Description
Your work will change lives. Including your own. The Opportunity At Recursion we are redefining drug discovery by uniting industrial-scale data generation with sophisticated computational models. We are seeking a visionary Head of DMPK to join our leadership team. You will lead the DMPK strategy to transition our internal and partnered programs from early hit-identification through to IND-enabling studies and early clinical development. But this is not a traditional DMPK role. You will be a key architect in an environment that is pushing the boundaries of “predict more, test less” - bridging the gap between high-throughput, experimentally derived data generation and predictive modeling. Your Impact - Strategic Leadership . Define and execute the overarching DMPK strategy for a diverse therapeutic area portfolio, primarily focused on small molecules with the agility to support emerging modalities ( e.g. peptides, ADCs, proximity-inducing therapeutics) - Scientific Rigor and Project Acceleration . Ensure high degree of scientific excellence as programs move from early discovery into development ensuring robust human dose projections, DDI assessments, and supporting translational PK/PD strategies. - Tech-Forward Collaboration . Partner with Data Science and ML teams to refine our predictive ADME models, transforming how we prioritize compounds and de-risking the portfolio. - External Partnerships . Act as a strategic subject matter expert for high-stakes external partnerships by collaborating with internal scientific leaders and external counterparts with transparency and technical rigor. - Talent Development . Develop and lead a high-performing team. You won't just manage - you will amplify the talents of your team, fostering an environment of active learning and rapid adaptation. - Cross-Functional Synergy . A critical component of multidisciplinary project teams. A critical partner to Toxicology, Translation and Design ensuring that DMPK insights are integrated into the earliest stages of target validation and lead optimization. Who You Are - The Academic Foundation: You hold a PhD (or equivalent) in Pharmacokinetics, Drug Metabolism, Pharmacology, or a related field. - The Industry Veteran: You have a proven track record of moving multiple programs from Discovery into Development (typically 15+ years) in the pharmaceutical or biotech industry. - The Nimble Mindset: You are comfortable working at the intersection of biology and technology. You are cautiously optimistic that data-driven, computational approaches are the future of drug discovery. - The Modality Expert: Deep expertise in small molecule DMPK is essential. Experience with related modalities (ADCs, proximity-inducing or peptides) is a distinct advantage. - The Regulatory Navigator: You are intimately familiar with IND submission requirements and have a history of successfully navigating regulatory interactions. - The Collaborative Leader: You value "One Team" over silos. You are kn